KCNIP2 Antikörper (AA 1-270)

Produktnummer ABIN7864996

Der Maus Monoklonal anti-KCNIP2 Antikörper (Klon KCNIP2-7588) (ABIN7864996) detektiert spezifisch KCNIP2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KCNIP2 Antikörper (AA 1-270) (ABIN7864996)

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KCNIP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KCNIP2-7588

Produktdetails anti-KCNIP2 Antikörper

Bindungsspezifität: AA 1-270

Verwendungszweck: KCNIP2 / KCHIP2 Antibody

Spezifität: In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4±-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99 % nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-270) of human KCNIP2 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu KCNIP2

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Andere Bezeichnung: KCNIP2

Hintergrund:

A type potassium channel modulatory protein 2, Cardiac voltage gated potassium channel modulatory subunit, DKFZp566L1246, KChIP2, Kcnip2, Kv channel interacting protein 2, Potassium channel interacting protein 2

Human brain.

Molekulargewicht: 27-36kDa

Gen-ID: 30819, 97044

UniProt: Q9NS61