Rekombinanter VEGF Antikörper (AA 1-200)
Kurzübersicht für Rekombinanter VEGF Antikörper (AA 1-200) (ABIN7858741)
Target
Alle VEGF Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-200
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Verwendungszweck
- Recombinant VEGF (Vascular Endothelial Growth Factor) Antibody
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Spezifität
- This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa1-200) of human VEGFA protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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Andere Bezeichnung
- VEGF
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Hintergrund
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MVCD1, Vascular Endothelial Growth Factor A (VEGF-A), Vascular Permeability Factor (VPF), VEGFA
breast or ovarian carcinomas.|Tumor cells in astrocytomas
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Molekulargewicht
- 19-22kDa (reducing) and 38kDa-44kDa (non-reducing)
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Gen-ID
- 7422, 73793
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UniProt
- P15692
Target
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