PON1 Antikörper (AA 1-200)

Produktnummer ABIN7864406

Dieser Maus Monoklonal Antikörper detektiert spezifisch PON1 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PON1 Antikörper (AA 1-200) (ABIN7864406)

Target: PON1 (Paraoxonase 1 (PON1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PON1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: PON1-1351

Produktdetails anti-PON1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: PON1 / Paraoxonase 1 Antibody

Spezifität: Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human PON1 protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu PON1

Target: PON1 (Paraoxonase 1 (PON1))

Andere Bezeichnung: PON1

Hintergrund:

A-esterase 1, Aromatic esterase 1, Arylesterase 1, Arylesterase B type, ESA, Esterase A, K 45, MVCD5, Paraoxonase 1, Paraoxonase B type, Paraoxonase, plasma, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1

Human liver.

Molekulargewicht: 43kDa

Gen-ID: 5444, 370995

UniProt: P27169