PAX4 Antikörper (AA 1-200)

Produktnummer ABIN7864377

Der Maus Monoklonal anti-PAX4 Antikörper wird verwendet zum Nachweis von PAX4 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für PAX4 Antikörper (AA 1-200) (ABIN7864377)

Target: PAX4 (Paired Box 4 (PAX4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: PAX4-7598

Produktdetails anti-PAX4 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: PAX4 Antibody

Spezifität: Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing ≤ cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ≤ cell lines MIN6, ≤ TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu PAX4

Target: PAX4 (Paired Box 4 (PAX4))

Andere Bezeichnung: PAX4

Hintergrund:

KPD, MODY9, Paired box 4

DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen

Molekulargewicht: 38kDa

Gen-ID: 5078, 129706

UniProt: O43316