Rekombinanter Keratin 6 Antikörper (AA 1-200)

Produktnummer ABIN7858596

Der Kaninchen Monoklonal anti-Keratin 6 Antikörper wird verwendet zum Nachweis von Keratin 6 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Keratin 6 Antikörper (AA 1-200) (ABIN7858596)

Target: Keratin 6 (KRT6)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Keratin 6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KRT6-8198R

Produktdetails anti-Keratin 6 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: Recombinant Cytokeratin 6 / KRT6 (Pan, a,b,c) (Basal Cell Marker) Antibody

Spezifität: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human KRT6 (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Keratin 6

Target: Keratin 6 (KRT6)

Andere Bezeichnung: Cytokeratin 6

Hintergrund:

CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II

Human tonsil or basal cell carcinoma (BCC).

Molekulargewicht: 56kDa

Gen-ID: 3853, 700779

UniProt: P02538