IL20RA Antikörper (AA 1-200)

Produktnummer ABIN7864480

Dieser Maus Monoklonal Antikörper detektiert spezifisch IL20RA in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IL20RA Antikörper (AA 1-200) (ABIN7864480)

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL20RA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IL20RA-1752

Produktdetails anti-IL20RA Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: IL20RA (Interleukin 20 Receptor Subunit Alpha) Antibody

Spezifität: The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human IL20RA protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu IL20RA

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Andere Bezeichnung: IL20RA

Hintergrund:

class II cytokine receptor ZCYTOR7, CRF2 8, Cytokine receptor class II member 8, Cytokine receptor family 2 member 8, IL 20R1, IL-20 receptor subunit alpha, IL-20R1, IL20 Receptor alpha, Interleukin 20 receptor alpha chain,

brain or psoriatic skin.|Human skin|testis

Molekulargewicht: 90-100kDa

Gen-ID: 53832, 445868

UniProt: Q9UHF4