IL18R1 Antikörper (AA 1-200)

Produktnummer ABIN7858556

Dieser Maus Monoklonal Antikörper detektiert spezifisch IL18R1 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IL18R1 Antikörper (AA 1-200) (ABIN7858556)

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL18R1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IL18R1-7593

Produktdetails anti-IL18R1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: IL18R1 Antibody

Spezifität: Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-é 79oΩ production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1± or IL-1≤. The association of IL-18 to IL-18R leads to activation of NFé 79oΩB. At present two subunits of IL-18R have been characterized: IL-18R± and IL-18R≤. IL-18R± has been described as the ligand-binding chain and IL-18R≤ as the signal-transduction chain.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human IL18R1 protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu IL18R1

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Andere Bezeichnung: IL18R1

Hintergrund:

CD218 antigen-like family member A, CDw218a antigen, IL-18R1, IL-1Rrp, IL1 receptor-related protein, Il18ralpha,IL1R-rp, IL1RRP, Interleukin 18 receptor, alpha chain

Human lung|leukocytes|liver or thymus.|spleen

Molekulargewicht: 62kDa

Gen-ID: 8809, 469521

UniProt: Q13478