HSD17B13 Antikörper (AA 1-200)

Produktnummer ABIN7858520

Dieser Maus Monoklonal Antikörper detektiert spezifisch HSD17B13 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HSD17B13 Antikörper (AA 1-200) (ABIN7858520)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSD17B13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: HSD17B13-13104

Produktdetails anti-HSD17B13 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: HSD17B13 / Hydroxysteroid 17-beta dehydrogenase 13 (NAFLD / NASH Marker) Antibody

Spezifität: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human HSD17B13 protein (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Andere Bezeichnung: HSD17B13

Hintergrund:

7-beta hydroxysteroid dehydrogenase, 17-beta-HSD 13, hepatic retinol/retinal dehydrogenase, short chain dehydrogenase/reductase family 16C member 3, short-chain dehydrogenase/reductase 9

Human liver, ovary, kidney, brain or bone marrow.

Molekulargewicht: 30kDa

Gen-ID: 345275

UniProt: Q7Z5P4