CEACAM1 Antikörper (AA 1-200)

Produktnummer ABIN7858370

Dieser Maus Monoklonal Antikörper detektiert spezifisch CEACAM1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CEACAM1 Antikörper (AA 1-200) (ABIN7858370)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: CEACAM1-12659

Produktdetails anti-CEACAM1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: CEACAM1 (CEA Cell Adhesion Molecule 1) / CD66a Antibody

Spezifität: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human CEACAM1 protein (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CEACAM1

Hintergrund:

Antigen CD66, BGP-1, BGPI, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), CD66a, CEACAM1, meconium antigen 100

Human colon, liver, endometrium or hepatic carcinoma tissues. SK-MEL-28 cells.

Molekulargewicht: 90-180kDa

Gen-ID: 634, 512682

UniProt: P13688