Cofilin 2 Antikörper (AA 1-166)
Kurzübersicht für Cofilin 2 Antikörper (AA 1-166) (ABIN7865261)
Target
Alle Cofilin 2 (CFL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-166
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Verwendungszweck
- CFL2 / NEM7 Antibody
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Spezifität
- Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa1-166) of human CFL2 protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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anti-Cofilin 2 (CFL2) (AA 57-166) antibody
CFL2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 6G9 unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyVerified CFL2 Reaktivität: Human, Ratte WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyCFL2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 121-153), (C-Term) antibodyCFL2 Reaktivität: Human, Maus, Ratte WB, IF, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 130-144), (C-Term) antibodyCFL2 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB48609 unconjugated
anti-Cofilin 2 (CFL2) antibodyCFL2 Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-156) antibodyCFL2 Reaktivität: Human WB, ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyCFL2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Pferd, Schwein, Affe, Fledermaus, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Cofilin 2 (CFL2)
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Andere Bezeichnung
- CFL2
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Hintergrund
- NEM7
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Molekulargewicht
- 19-21kDa
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Gen-ID
- 1073, 180141
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UniProt
- Q9Y281
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Pathways
- Caspase Kaskade in der Apoptose
Target
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