LGALS13 Antikörper (AA 1-139)
Kurzübersicht für LGALS13 Antikörper (AA 1-139) (ABIN7858253)
Target
Alle LGALS13 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-139
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Verwendungszweck
- Galectin-13 (GAL13) / Placental Protein 13 (PP13) Antibody
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Spezifität
- It recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ≤-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant human Galectin-13 protein fragment (aa1-139) (exact sequence is proprietary)
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
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Andere Bezeichnung
- Galectin-13
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Hintergrund
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Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13
K-562 cells. Placenta or Spleen.
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Molekulargewicht
- 16kDa (monomer), 32kDa (homodimer)
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Gen-ID
- 29124, 23671
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UniProt
- Q9UHV8
Target
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