Fatty Acid Binding Protein Antikörper (AA 1-127)

Produktnummer ABIN7858193

Dieser Maus Monoklonal Antikörper detektiert spezifisch Fatty Acid Binding Protein in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Fatty Acid Binding Protein Antikörper (AA 1-127) (ABIN7858193)

Target: Fatty Acid Binding Protein (FABP)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fatty Acid Binding Protein Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: FABP1-3483

Produktdetails anti-Fatty Acid Binding Protein Antikörper

Bindungsspezifität: AA 1-127

Verwendungszweck: Fatty Acid Binding Protein (Liver) / FABP1 Antibody

Spezifität: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Fatty Acid Binding Protein

Target: Fatty Acid Binding Protein (FABP)

Andere Bezeichnung: Fatty Acid Binding Protein

Hintergrund:

FABP1, L-FABP

Liver or colon carcinoma tissues (IHC). Kidney tissue lysates (WB).

Molekulargewicht: 14kDa

Gen-ID: 2168, 380135

UniProt: P07148

Pathways: Chromatin Binding, Monocarboxylic Acid Catabolic Process