Rekombinanter MYH11 Antikörper (AA 1-100)

Produktnummer ABIN7863178

Der Kaninchen Monoklonal anti-MYH11 Antikörper wird verwendet zum Nachweis von MYH11 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter MYH11 Antikörper (AA 1-100) (ABIN7863178)

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MYH11 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MYH11-4337R

Produktdetails anti-MYH11 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: Recombinant Smooth MuscleMyosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) Antibody

Spezifität: Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human fragment corresponding to Myosin residues within aa1-100 of Myosin (Smooth Muscle)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MYH11

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Andere Bezeichnung: Smooth MuscleMyosin Heavy Chain

Hintergrund:

AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC

Human smooth muscle, uterus or breast.

Molekulargewicht: 227kDa

Gen-ID: 4629, 460109

UniProt: P35749