Rekombinanter HBA1 Antikörper (AA 1-100)

Produktnummer ABIN7864747

Der Maus Monoklonal anti-HBA1 Antikörper wird verwendet zum Nachweis von HBA1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter HBA1 Antikörper (AA 1-100) (ABIN7864747)

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HBA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RHBA-9167

Produktdetails anti-HBA1 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: Recombinant Hemoglobin alpha (2 chain) Antibody

Spezifität: Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The ± (16p13.3; 5'-é 79oΩ-pseudoé 79oΩ-pseudo±2-pseudo±1-±2-±1- é 79oΩ1-3') and ≤ (11p15.5) globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two ± chains and two ≤ chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between ± and ≤ chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the ±1-≤2 cleavage plane. When the two ±1-≤2 interfaces are closely bound, Hgb has a low affinity for oxygen. Hb A, which contains two ± chains plus two ≤ chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two ± chains plus two d chains, and fetal hemoglobin (Hb F), which consists of two ± chains together with two g chains.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-100) of human HBA2 protein (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Andere Bezeichnung: Hemoglobin alpha

Hintergrund:

Alpha 1 globin, HBA1, HBA2, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin subunit alpha

Human spleen, stomach cancer, lung or placenta.

Molekulargewicht: 16kDa

Gen-ID: 3039, 449630

UniProt: P69905