Rekombinanter Desmin Antikörper

Produktnummer ABIN7862702

Dieser Maus Monoklonal Antikörper detektiert spezifisch Desmin in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Huhn und Hamster.

Kurzübersicht für Rekombinanter Desmin Antikörper (ABIN7862702)

Target: Desmin (DES)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Maus, Huhn, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RDES-1711

Produktdetails anti-Desmin Antikörper

Expressionssystem: HEK-293 Cells

Verwendungszweck: Recombinant Desmin (Muscle Cell Marker) Antibody

Spezifität: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain °™-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Aufreinigung: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant full-length human desmin protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Human uterus or leiomyosarcoma. Heart, Intestine or RH30.

Molekulargewicht: 52kDa

Gen-ID: 1674, 594952

UniProt: P17661