Rekombinanter TGFBR1 Antikörper

Produktnummer ABIN7857831

Der Maus Monoklonal anti-TGFBR1 Antikörper wird verwendet zum Nachweis von TGFBR1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter TGFBR1 Antikörper (ABIN7857831)

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TGFBR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RG3E6

Produktdetails anti-TGFBR1 Antikörper

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant Transforming Growth Factor Beta Receptor 1 (TGFBR1) Antibody

Spezifität: Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu TGFBR1

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Andere Bezeichnung: Transforming Growth Factor Beta Receptor 1

Hintergrund:

ALK5 | SKR4

Human placenta, spleen or liver. HEK293T cells.

Molekulargewicht: 53kDa

Gen-ID: 7046

UniProt: P36897

Pathways: Growth Factor Binding