Rekombinanter Selectin E/CD62e Antikörper

Produktnummer ABIN7857825

Der Maus Monoklonal anti-Selectin E/CD62e Antikörper wird verwendet zum Nachweis von Selectin E/CD62e in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter Selectin E/CD62e Antikörper (ABIN7857825)

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Selectin E/CD62e Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: R16G4

Produktdetails anti-Selectin E/CD62e Antikörper

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant CD62E / Selectin E (SELE) / ELAM-1 Antibody

Spezifität: CD62E is also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) or E-selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). CD62E is expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial tethering and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. The main ligands recognized by CD62E are oligosaccharides related to sialyl-lewis X.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant fusion protein corresponding to the cysteine-rich complement control protein domains of the CD62E molecule

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Andere Bezeichnung: CD62E

Hintergrund:

CD62E, ELAM1, SELE, E-selectin, ELAM-1, LECAM2

Human bone marrow, lymph node, inflamed tonsil, heart or liver.

Molekulargewicht: 115kDa

Gen-ID: 6401

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling