Laminin gamma 1 Antikörper

Produktnummer ABIN7857806

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Laminin gamma 1 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Laminin gamma 1 Antikörper (ABIN7857806)

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Laminin gamma 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: LAMC1-13970R

Produktdetails anti-Laminin gamma 1 Antikörper

Expressionssystem: CHO Cells

Verwendungszweck: Laminin, gamma 1 (LAMC1) Antibody

Spezifität: Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant human full-length LAMC1 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Laminin gamma 1

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Andere Bezeichnung: Laminin, gamma 1

Hintergrund:

LAMB2, LAMC1, Laminin B2 chain, Laminin gamma 1, Laminin gamma 1 chain

Normal colon or carcinomas.

Molekulargewicht: 210kDa

Gen-ID: 3915

UniProt: P11047