Rekombinanter SV2A Antikörper (Cytoplasmic Domain, N-Term)

Produktnummer ABIN7857725

Dieser Maus Monoklonal Antikörper detektiert spezifisch SV2A in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter SV2A Antikörper (Cytoplasmic Domain, N-Term) (ABIN7857725)

Target: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SV2A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: R15E11

Produktdetails anti-SV2A Antikörper

Bindungsspezifität: Cytoplasmic Domain, N-Term

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant Synaptic Vesicle Protein 2 (SV2) (Marker of Neuroendocrine Cells) Antibody

Spezifität: Synaptic vesicle protein 2 (SV2) is an integral membrane glycoprotein. It is required for normal neurotransmission and may play a role in the regulation of calcium-stimulated exocytosis. SV2 exists in three forms, SV2A, SV2B and SV2C, each containing 12 transmembrane spanning regions. SV2 proteins are among the most abundant and conserved components of synaptic vesicles in vertebrates. They are present on all small synaptic vesicles independent of transmitter type. SV2A and SV2B are widely distributed in the nervous system, whereas SV2C is only observed in a small number of neurons in a few areas of the brain. SV2A is expressed at the highest levels in subcortical regions, whereas the highest level of expression of SV2B is in the cortex and hippocampus. SV2 is expressed on secretory vesicles of neuroendocrine cells in the GI tract, pancreas, anterior pituitary gland, thyroid, parathyroid and adrenal medulla and also in exocrine chief cells of gastric mucosa.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to the N-terminal cytoplasmic domain of the human synaptic vesicle 2A molecule which shares some regions of homology with the SV2B molecule

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu SV2A

Target: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Andere Bezeichnung: Synaptic Vesicle Protein 2

Hintergrund:

KIAA0736 | PSEC0174 | SV2A | Synaptic vesicle glycoprotein 2A

Human brain.

Molekulargewicht: 93kDa

Gen-ID: 9900

UniProt: Q7L0J3