Rekombinanter FOXP1 Antikörper (AA 350-450)
Kurzübersicht für Rekombinanter FOXP1 Antikörper (AA 350-450) (ABIN7857656)
Target
Alle FOXP1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 350-450
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Expressionssystem
- CHO Cells
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Verwendungszweck
- Recombinant FOXP1 (Transcription Factor) Antibody
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Spezifität
- Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 79oΩ 79oΩ80 % ) for FOXP1 is needed to achieve high specificity for the ABC subtype.
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Aufreinigung
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogen
- Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- FOXP1 (Forkhead Box P1 (FOXP1))
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Andere Bezeichnung
- FOXP1
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Hintergrund
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Fork head related protein like B, Forkhead box protein P1 (FOXP1), Glutamine rich factor 1, hFKH1B, HSPC215, QRF1
Human tonsil or colon. Ramos
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Molekulargewicht
- 75kDa
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Gen-ID
- 27086
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UniProt
- Q9H334
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Pathways
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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