Rekombinanter MUC4 Antikörper (AA 1729-1860)

Produktnummer ABIN7857631

Der Kaninchen Monoklonal anti-MUC4 Antikörper (Klon MUC4-8660R) (ABIN7857631) detektiert spezifisch MUC4 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter MUC4 Antikörper (AA 1729-1860) (ABIN7857631)

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MUC4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MUC4-8660R

Produktdetails anti-MUC4 Antikörper

Bindungsspezifität: AA 1729-1860

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant MUC4 (Mucin 4 / Gastric Mucin) Antibody

Spezifität: The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa 1729-1860) of human MUC4 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Andere Bezeichnung: MUC4 Mucin 4

Hintergrund:

Ascites sialoglycoprotein 1 / 2, ASGP, ASGP-1, ASGP-2, MUC-4, MUC4, Mucin 4 cell surface associated, Mucin 4 tracheobronchial, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin

Human stomach, colon or esophagus.

Molekulargewicht: 235kDa

Gen-ID: 4585, 369646

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity