Rekombinanter MBP Antikörper (AA 1-100)

Produktnummer ABIN7857597

Der Maus Monoklonal anti-MBP Antikörper wird verwendet zum Nachweis von MBP in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter MBP Antikörper (AA 1-100) (ABIN7857597)

Target: MBP (Myelin Basic Protein (MBP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RMBP-9431

Produktdetails anti-MBP Antikörper

Bindungsspezifität: AA 1-100

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant Myelin Basic Protein Antibody

Spezifität: Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. rMBP/9301 is used in clinical diagnostics to detect MBP levels or myelination in human MBP. rMBP/9301 is used in a two-site ELISA with clone MBP/4273. Both are used interchangeably as capture and detection antibody.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa1-100) of human MBP protein (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu MBP

Target: MBP (Myelin Basic Protein (MBP))

Andere Bezeichnung: Myelin Basic Protein

Hintergrund:

GDB, Golli MBP, myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MLD, Myelin A1 Protein, basic, Myelin Deficient, Myelin membrane encephalitogenic protein, SHI, Shiverer, SP

Human brain or astrocytoma tissue.

Molekulargewicht: 13-21kDa

Gen-ID: 4155, 551713

UniProt: P02686