Granzyme D/B/E/N/G/F/H (AA 151-252) Antikörper (HRP)

Produktnummer ABIN742359

Produktdetails

Target: Granzyme D/B/E/N/G/F/H

Bindungsspezifität: AA 151-252

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: Western Blotting (WB), ELISA

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Granzyme D/B/E/N/G/F/H

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Granzyme D/B/E/N/G/F/H

Hintergrund:

Synonyms: Granzyme D, Granzyme B, Granzyme E, Granzyme N, Granzyme G, Granzyme F, Granzyme H, Cathepsin G-like 2, CCP-X, CCP3, CCP4, CCP5, CGL-2, CSP-C, Ctla-5, Ctla-6, Ctla-7, CTLA1, CTSGL2, Grz d, Grz e, Grz f, Grz g, GZMD, Gzme, Gzmf, Gzmg, GZMH, MCSP-2, MCSP-3, MGC117682, Rnkp7, mast cell proteinase-3-like, Cytotoxic T-lymphocyte proteinase, Granzyme H precursor, Cytotoxic serine protease-C, CSP-C.

Background: protease required for lymphocyte cytotoxic granules to lyse target cells [RGD]. Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.

Gen-ID: 2999