CXCL13 Antikörper (AA 23-109)

Produktnummer ABIN741960

Dieser Anti-CXCL13 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CXCL13 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für CXCL13 Antikörper (AA 23-109) (ABIN741960)

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CXCL13 Antikörper

Bindungsspezifität: AA 23-109

Kreuzreaktivität: Human, Maus

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXCL13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CXCL13 Antikörper (ABIN741960)

Li, Cao, Wang, Jia, He, Zhang: "Up-regulation of chemokine CXCL13 in systemic candidiasis." in: Clinical immunology (Orlando, Fla.), (2018) (PubMed).

Lemma, Pasanen, Haapasaari, Sippola, Sormunen, Soini, Jantunen, Koivunen, Salokorpi, Bloigu, Turpeenniemi-Hujanen, Kuittinen: "Similar chemokine receptor profiles in lymphomas with central nervous system involvement - possible biomarkers for patient selection for central nervous system prophylaxis, a retrospective study." in: European journal of haematology, (2015) (PubMed).

Nakamura, Ito, Kobayashi, Herndon, Suzuki: "Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype." in: Cytokine, Vol. 73, Issue 1, pp. 8-15, (2015) (PubMed).

Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: "Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 9, Issue 2, pp. 255-64, (2014) (PubMed).

Pimenta, De, Weiss, Feng, Hall, Kilic, Bhanot, Ganesan, Ran, Barnes: "IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5(+) B- and T-cell trafficking to tumor-conditioned media." in: Immunology and cell biology, (2014) (PubMed).

Details zu CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Andere Bezeichnung: CXCL13/BCA1

Hintergrund:

Synonyms: BLC, BCA1, ANGIE, BCA-1, BLR1L, ANGIE2, SCYB13, C-X-C motif chemokine 13, B cell-attracting chemokine 1, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, CXCL13

Background: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.

Gen-ID: 10563

UniProt: O43927