SLAMF7 Antikörper (AA 51-160) (Cy7)

Produktnummer ABIN741831

Dieses Anti-SLAMF7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SLAMF7 in WB und FACS. Geeignet für Human und Maus.

Kurzübersicht für SLAMF7 Antikörper (AA 51-160) (Cy7) (ABIN741831)

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLAMF7 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-SLAMF7 Antikörper (Cy7)

Bindungsspezifität: AA 51-160

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLAMF7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLAMF7

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Andere Bezeichnung: Slamf7/Cd319/Cs1

Hintergrund:

Synonyms: 19A, 19A24 protein, CD 319, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CD319, CD319 antigen, CRACC, CS1, Membrane protein FOAP 12, Novel Ly9, Novel LY9 lymphocyte antigen 9 like protein, Protein 19A, SLAM family member 7, SLAMF 7.

Background: SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

UniProt: Q9NQ25