TTR Antikörper

Produktnummer ABIN7833608

Der Maus Monoklonal anti-TTR Antikörper (ABIN7833608) detektiert spezifisch TTR in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TTR Antikörper (ABIN7833608)

Target: TTR (Transthyretin (TTR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-TTR Antikörper

Verwendungszweck: Anti-Transthyretin 56-61, amyloid specific (mouse monoclonal)

Kreuzreaktivität (Details): Human Transthyretin Amyloids
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Aufreinigung: Affinity purified

Immunogen: Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE The epitope has been mapped to residue 56-61

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: 1:1000 (ELISA), 1:500 (IHC), 1:1000 (WB)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 μL sterile water to reconstitute to 1 mg/mL

Buffer: Affinity purified in PBS pH 7.4.

Handhabung: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Lagerung: 4 °C

Informationen zur Lagerung: Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Transthyretin 56-61

Hintergrund: Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 10 % of the population above 80 years of age with depositions mainly found in the heart.Monoclonal IgG1 antibody. Amyloid specific for human Transthyretin. Detects the C-terminal fragment 49-127 frequently formed in vivo.

Molekulargewicht: 155

Pathways: Hormone Transport