GLP1R Antikörper

Produktnummer ABIN7852237

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch GLP1R in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GLP1R Antikörper (ABIN7852237)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GLP1R Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 1A4

Produktdetails anti-GLP1R Antikörper

Verwendungszweck: Anti-GLP1R antibody(1A4), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Haltbarkeit: 12 months

Details zu GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Andere Bezeichnung: GLP1R

Hintergrund: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

UniProt: P43220

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour