GLP1R Antikörper
Kurzübersicht für GLP1R Antikörper (ABIN7829623)
Target
Alle GLP1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-GLP1R antibody(1A4), Rabbit mAb
-
Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Flow Cyt 1/100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
-
Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
-
Haltbarkeit
- 12 months
-
-
- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
-
Andere Bezeichnung
- GLP1R
-
Hintergrund
- This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
-
UniProt
- P43220
-
Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
Target
-