Rekombinanter CXCR4 Antikörper

Produktnummer ABIN7851131

Dieser Human Chimeric Antikörper detektiert spezifisch CXCR4 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CXCR4 Antikörper (ABIN7851131)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Antikörpertyp: Recombinant Antibody

Fragment: Fc fragment

Reaktivität: Human

Wirt: Human, Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: DMC680

Produktdetails anti-CXCR4 Antikörper

Verwendungszweck: Anti-CXCR4 antibody(DMC680), IgG1 Chimeric mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

UniProt: P61073, A0A0U3FJG0, A0A0U3GXA9

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events