LY75/DEC-205 Antikörper

Produktnummer ABIN7828842

Der Ratte Monoklonal anti-LY75/DEC-205 Antikörper (Klon NLDC-145) (ABIN7828842) detektiert spezifisch LY75/DEC-205 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für LY75/DEC-205 Antikörper (ABIN7828842)

Target: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LY75/DEC-205 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: NLDC-145

Produktdetails anti-LY75/DEC-205 Antikörper

Verwendungszweck: AF/LE Purified Anti-Mouse CD205 Antibody[NLDC-145]

Aufreinigung: >98%, Protein A/G purified

Reinheit: >98 %

Immunogen: Recombinant Mouse CD205 protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: FCM 2 μg/mL(0.5x106-1x106 cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Konservierungsmittel: Without preservative

Handhabung: This preparation contains no preservatives, thus it should be handled under aseptic conditions

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Haltbarkeit: 12 months

Details zu LY75/DEC-205

Target: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Andere Bezeichnung: CD205

Hintergrund: Cd205,Ly75,DEC-205,Ly-75,CD205, also known as DEC-205, is a 205 kD integral membrane protein homologous to the macrophage mannose receptor. It is a type I cell surface protein that belong to the C-type lectin family. CD205 is expressed at high levels by dendritic cells and thymic epithelial cells. It is also expressed by a number of other cell types, such as B lymphocytes, macrophages, Langerhans cells, bone marrow stromal cells, granulocytes, epithelial cells of pulmonary airways, and the capillaries of the brain. CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing. It mediates antigen uptake and presentation and cross-presentation to T cells. It has been reported that CD205 acts as a recognition receptor for dying cells, potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance. Antibody-mediated antigen-targeting via the DEC-205 receptor increases the efficiency of vaccination for T cell immunity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q60767