Rekombinanter ZNF259 Antikörper

Produktnummer ABIN7828682

Der Kaninchen Monoklonal anti-ZNF259 Antikörper wird verwendet zum Nachweis von ZNF259 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Rekombinanter ZNF259 Antikörper (ABIN7828682)

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ZNF259 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A747

Produktdetails anti-ZNF259 Antikörper

Verwendungszweck: Recombinant ZPR1 Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu ZNF259

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Andere Bezeichnung: ZPR1

Hintergrund: ZPR,MGC,Zinc finger protein,Zinc finger protein ZPR,ZNF,ZPR1,ZNF259,MGC110983,Zinc finger protein 259,Zinc finger protein ZPR1,ZNF 259,The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the receptor (1). ZPR1 translocates from the cytoplasm to nucleus following mitogen (i.e. EGF) stimulation (2,3). ZPR1 also interacts with translation elongation factor eEF1A in vivo following EGF treatment (3). The interaction between the zinc finger protein and elongation factor is important for cell proliferation. Cells lacking ZPR1 exhibit abnormal nucleolar function, suggesting that ZPR1 is required for cell viability and nucleolar function in dividing cells (3). ZPR1 knockout mice exhibit significant neurodegeneration, and reduced or altered expression of ZPR1 may contribute to spinal muscular atrophy, a disorder characterized by degeneration of spinal cord neurons (4). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 51 kDa

Observed MW: 53 kDa The actual band is not consistent with the expectation.

UniProt: O75312