Rekombinanter WT1 Antikörper

Produktnummer ABIN7828676

Der Kaninchen Monoklonal anti-WT1 Antikörper wird verwendet zum Nachweis von WT1 in Proben von Human, Ratte und Maus. Er wurde validiert für IHC und WB.

Kurzübersicht für Rekombinanter WT1 Antikörper (ABIN7828676)

Target: WT1 (Wilms Tumor 1 (WT1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser WT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: A742

Produktdetails anti-WT1 Antikörper

Verwendungszweck: Recombinant WT1 Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:10000,IHC 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1

Hintergrund: AWT,FWT,NPHS,EWS-WT,WIT,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,FWT1,Wilms Tumor,Wilms tumor 1,Wilms' tumor gene,Wilms tumor protein,Wilms' tumor protein,WIT 2,WIT2,WT,WT 1,WIT 2, WT 1,AWT1,FWT1,GUD,NPHS4,WAGR,Wilms tumor 1,Wilms Tumor,Wilms tumor protein,Wilms' tumor gene,Wilms' tumor protein,WIT2,WT,WT1,WT1,WT33,Wilms' Tumor protein (WT1) is a transcription factor named from Wilms' Tumor 1, an embryonal malignancy of the kidneys that is caused by mutations in the WT1 gene. It is highly important in development, particularly of the genitourinary system, and mutations and dysregulation of expression of WT1 result in a variety of syndromes affecting the genitourinary system and other tissues.WT1 has a myriad of biological functions and a host of interacting partners and target genes. It can behave as a transcriptional activator, or a repressor, and can act as an oncogene or a tumor suppressor. It exerts influence over the epigenetic landscape, and also has post translational influence of gene expression through RNA interactions. The diverse biological roles of WT1 have been attributed to the existence of multiple isoforms and post translation modifications of the protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 49 kDa

Observed MW: 52 kDa The actual band is not consistent with the expectation.

UniProt: P19544

Pathways: Tube Formation