Rekombinanter SV2A Antikörper

Produktnummer ABIN7828606

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch SV2A in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter SV2A Antikörper (ABIN7828606)

Target: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SV2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A710

Produktdetails anti-SV2A Antikörper

Verwendungszweck: Recombinant SV2A Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000,IHC 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu SV2A

Target: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Andere Bezeichnung: SV2A

Hintergrund: KIAA,PSEC,SV2,SV2A,KIAA0736,PSEC0174,SV2s are a family of synaptic vesicle proteins expressed in both neurons and endocrine cells. SV2s function in the regulation of synaptic vesicle traffic, cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation and the facilitation of synaptic transmission. There are three isoforms of SV2: SV2A, SV2B and SV2C. Each of these isoforms are structured similarly but expressed varyingly. SV2C, a minor isoform of SV2, expressed in a small subset of neurons located within the basal forebrain, midbrain and brainstem. SV2B, a major isoform of SV2 is expressed more abundantly, although rarely without the coexpression of SV2A. SV2A, the other major isoform of SV2 is the most widely expressed. SV2A is located in the presynaptic nerve terminals of almost every neuron throughout the nervous system. In addition, it is also located in most neuroendocrine secretory granules. SV2A has been identified as a critical protein for proper function of the central nervous system and has been linked to the physiopathology of epilepsy. In addition to the epileptic affects of this protein, mutations in it have also been seen to result in schizophrenia. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 83 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q7L0J3