Rekombinanter SIRT6 Antikörper
Kurzübersicht für Rekombinanter SIRT6 Antikörper (ABIN7828568)
Target
Alle SIRT6 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant SIRT6 Monoclonal Antibody
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Aufreinigung
- Protein A purified
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Immunogen
- Recombinant human SIRT6 fragment
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Isotyp
- IgG, kappa
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Applikationshinweise
- WB 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- SIRT6 (Sirtuin 6 (SIRT6))
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Andere Bezeichnung
- SIRT6
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Hintergrund
- SIRT,SIR2L,sirtuin,SIR2L6,SIRT6,sirtuin 6,SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway. The BER pathway repairs single-stranded DNA lesions that arise spontaneously from endogenous alkylation, oxidation, and deamination events. SirT6 deficient mice show increased sensitivity to DNA-damaging agents, including the alkylating agents MMS and H2O2. In addition, these mice show genome instability with increased frequency of fragmented chromosomes, detached centromeres, and gaps. SirT6 may regulate the BER pathway by deacetylating DNA Polβ or other core components of the pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molekulargewicht
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Calculated MW: 39 kDa
Observed MW: 42 kDa The actual band is not consistent with the expectation.
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UniProt
- Q8N6T7
Target
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