Rekombinanter SETD1A Antikörper

Produktnummer ABIN7828559

Der Kaninchen Monoklonal anti-SETD1A Antikörper wird verwendet zum Nachweis von SETD1A in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, IF und FACS.

Kurzübersicht für Rekombinanter SETD1A Antikörper (ABIN7828559)

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SETD1A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: A256

Produktdetails anti-SETD1A Antikörper

Verwendungszweck: Recombinant SETD1A Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human SETD1A fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100,IF 1:100-1:500,FCM 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu SETD1A

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Andere Bezeichnung: SETD1A

Hintergrund: Set,KIAA,Set1,KMT2F,Set1A,SETD1A,KIAA0339,Histone-lysine N-methyltransferase SETD1A,hSET1A,KMT2F,Lysine N methyltransferase 2F,Lysine N-methyltransferase 2F,SET domain containing 1A,SET domain containing protein 1A,SET domain-containing protein 1A,SET1,Set1 Ash2 histone methyltransferase complex subunit SET1,Set1/Ash2 histone methyltransferase complex subunit SET1,SET1A,hSET1 is a component of the histone methyltransferase (HMT) complex, which is a member of the COMPASS family, has H3K4 methyltransferase activity, and is closely related to development and tumors. hSET1 can produce mono-, di- and Trimethylation at lys4 (K4) on histone H3. This activity is blocked by the pre-methylation of the transcription repressor K9, indicating that the SET1/ASH2 complex can cause crosstalk between K9 methylation and K4 methylation. SET1 protein may play a role in synaptic function and neuron development. In addition, hSET1 protein can affect the proliferation and apoptosis of leukemia cells, and promote differentiation into neutrophils, providing new ideas for the treatment of leukemia and other cancers. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: O15047