Rekombinanter PRMT5 Antikörper

Produktnummer ABIN7828493

Der Kaninchen Monoklonal anti-PRMT5 Antikörper wird verwendet zum Nachweis von PRMT5 in Proben von Human. Er wurde validiert für WB, IHC und IP.

Kurzübersicht für Rekombinanter PRMT5 Antikörper (ABIN7828493)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PRMT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: A338

Produktdetails anti-PRMT5 Antikörper

Verwendungszweck: Recombinant PRMT5 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PRMT5 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:10000,IHC 1:50-1:100,IP 1:25-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Andere Bezeichnung: PRMT5

Hintergrund: IBP,JBP,SKB,PRMT,HRMT1L,HRMT1L5,IBP72,JBP1,SKB1,SKB1Hs,PRMT5,72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,homolog of,Jak-binding protein 1,JBP 1,PRMT 5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. cerevisiae,S. POMBE,S. POMBE HOMOLOG OF,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase/binding protein 1,Shk1 kinase-binding protein 1 homolog,SKB 1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe),Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 73 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development