Rekombinanter PEG10 Antikörper

Produktnummer ABIN7828446

Der Kaninchen Monoklonal anti-PEG10 Antikörper (Klon A675) (ABIN7828446) detektiert spezifisch PEG10 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter PEG10 Antikörper (ABIN7828446)

Target: PEG10 (Paternally Expressed 10 (PEG10))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PEG10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A675

Produktdetails anti-PEG10 Antikörper

Verwendungszweck: Recombinant PEG10 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PEG10 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Andere Bezeichnung: PEG10

Hintergrund: PEG,RTL,Mart,RGAG,SIRH,KIAA,PEG10,EDR,HB-1,MEF3L,2-Mar,Mart2,RGAG3,RTL2,SIRH1,KIAA1051,MEF3L1,Paternally expressed gene 10(PEG10 ) is an imprinted gene which is derived from a Ty3/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. The PEG10 gene has two overlapping open reading frames that are regulated by the programmed process of -1 frameshifting. The first encoded protein ORF1 (or RF1) has a Gag domain with coiled-coil domain and zinc finger domains, while ORF1-2 (or RF1/RF2) is produced by -1 frameshifting and creates a fusion of the ORF1 Gag domain with a carboxyl-terminal Pol-like protease domain. PEG10 has retained the ability to form virus-like particles (VLPs) that are secreted as small extracellular vesicles delivered to distant sites. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 55/100 kDa

Observed MW: 55/100 kDa

UniProt: Q86TG7