Rekombinanter PAX8 Antikörper

Produktnummer ABIN7828439

Der Kaninchen Monoklonal anti-PAX8 Antikörper wird verwendet zum Nachweis von PAX8 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC und IF.

Kurzübersicht für Rekombinanter PAX8 Antikörper (ABIN7828439)

Target: PAX8 (Paired Box 8 (PAX8))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PAX8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A323

Produktdetails anti-PAX8 Antikörper

Verwendungszweck: Recombinant PAX8 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PAX8 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Andere Bezeichnung: PAX8

Hintergrund: Paired box,Paired box gene,Paired domain gene,paired box homeotic gene,PAX,PAX8,OTTHUMP00000158659,OTTHUMP00000158660,OTTHUMP00000203723,OTTHUMP00000203724,Paired box 8,Paired box gene 8,paired box homeotic gene 8,Paired box protein Pax 8,Paired box protein Pax-8,Paired domain gene 8,PAX 8,PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96 % of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q06710

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation