Rekombinanter MUC1 Antikörper

Produktnummer ABIN7828401

Der Kaninchen Monoklonal anti-MUC1 Antikörper (Klon A309) (ABIN7828401) detektiert spezifisch MUC1 in IHC und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter MUC1 Antikörper (ABIN7828401)

Target: MUC1 (Mucin 1 (MUC1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MUC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: A309

Produktdetails anti-MUC1 Antikörper

Verwendungszweck: Recombinant MUC1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human MUC1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu MUC1

Target: MUC1 (Mucin 1 (MUC1))

Andere Bezeichnung: MUC1

Hintergrund: MAM,CA 15,MUC,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,CA15 3,CA153,Episialin,Carcinoma associated mucin,MUC 1,MUC1 beta,MUC1 CT,MUC1 NT,Mucin 1,Peanut reactive urinary mucin,Polymorphic epithelial mucin,Tumor associated mucin,MUC1/CA15-3 C-terminal,EMA,mucin 1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,Carcinoma-associated mucin,Krebs von den Lungen-6,Peanut-reactive urinary mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin,The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 17 kDa

Observed MW: 24 kDa The actual band is not consistent with the expectation.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling