Rekombinanter MTAP Antikörper

Produktnummer ABIN7828387

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch MTAP in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter MTAP Antikörper (ABIN7828387)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MTAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A519

Produktdetails anti-MTAP Antikörper

Verwendungszweck: Recombinant MTAP Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human MTAP fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:3000,IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Andere Bezeichnung: MTAP

Hintergrund: HEL,MTAP,BDMF,DMSFH,DMSMFH,HEL-249,LGMBF,MSAP,c86fus,5' methylthioadenosine phosphorylase,5''-methylthioadenosine phosphorylase,Epididymis luminal protein 249,HEL 249,MeSAdo phosphorylase,Methylthioadenosine phosphorylase,MTA phosphorylase,MTAPase,S methyl 5 thioadenosine phosphorylase,S methyl 5' thioadenosine phosphorylase,S-methyl-5''-thioadenosine phosphorylase,MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5'-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. MTAP is expressed in all normal cells and tissues, although frequently lost in different human tumors including pancreatic adenocarcinoma, neuroendocrine tumors, non-small cell lung carcinoma and breast carcinoma, thereby implicating its potential function as a tumor suppressor. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 31 kDa

Observed MW: 31 kDa

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process