Rekombinanter Histone H4 Antikörper (H4K12ac)

Produktnummer ABIN7828287

Der Kaninchen Monoklonal anti-Histone H4 Antikörper (Klon A106) (ABIN7828287) detektiert spezifisch Histone H4 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter Histone H4 Antikörper (H4K12ac) (ABIN7828287)

Target: Histone H4

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Histone H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A106

Produktdetails anti-Histone H4 Antikörper

Bindungsspezifität: H4K12ac

Verwendungszweck: Recombinant Histone H4 (Acetyl Lys12) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Acetylated human histone H4 (Lys12) peptide

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Histone H4

Target: Histone H4

Hintergrund: H4F,methyl histone H,methylated histone H,HIST2H,HIST1H,HISTH4H,histone H,HIST2H4B,H4/o,histone H4,HIST1H4A,FO108,H4/p,HIST1H4,Hist4h4,HISTH4H4,methyl histone H4,methylated histone H4,H4/A,H4FA,H4/I,H4FI,HIST1H4B,H4/G,H4FG,HIST1H4C,H4/B,H4FB,HIST1H4D,H4/J,H4FJ,HIST1H4E,H4/C,H4FC,HIST1H4F,H4/H,H4FH,HIST1H4H,H4/M,H4FM,HIST1H4I,H4/E,H4FE,H4/D,H4FD,HIST1H4K,H4/K,H4FK,HIST1H4L,H4/N,H4F2,H4FN,HIST2H4,HIST2H4A,H4,H4C1,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4C11,H4C12,H4C13,H4C14,H4C15,H4-16,A,I,H4B,H4J,H4H,H4M,H4E,HIST1H4J,H4D,H4C,H4/p,histone H4,HIST1H4B H4/I,Histone post-translational modifications (PTMs), known as the ""histone code"", are key mechanisms of epigenetics that modulate chromatin structures. The PTMs on histone including acetylation, methylation, phosphorylation, and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability and gene transcription. Histone acetylation, tightly controlled by the opposing action of histone acetyltransferases (HATs) and histone deacetylases (HDACs), occurs primarily at lysine residues on the N-terminal tails of histones H2A (Lys5, 9, and 15), H2B (Lys5, 12, 15, 16, and 20), H3 (Lys4, 9, 14, 18, 23, 27, and 36), and H4 (Lys5, 8, 12, 16, and 20), and plays vital roles in the regulation of gene expression, DNA damage repair, chromatin dynamics, etc. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 11 kDa

Observed MW: 11 kDa

UniProt: P62805