Rekombinanter HSPE1 Antikörper

Produktnummer ABIN7828249

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch HSPE1 in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter HSPE1 Antikörper (ABIN7828249)

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HSPE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A193

Produktdetails anti-HSPE1 Antikörper

Verwendungszweck: Recombinant Cpn10 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human Cpn10 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:200-1:1000,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu HSPE1

Target: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Andere Bezeichnung: Cpn10

Hintergrund: CPN,HSP,HSPE,HSPE1,CPN10,EPF,GROES,HSP10,10 kDa chaperonin,10 kDa heat shock protein,10 kDa heat shock protein mitochondrial,CH10,Chaperonin 10,Chaperonin 10 homolog,cpn10 homolog,Early pregnancy factor,Early-pregnancy factor,GroES homolog,Heat shock 10kD protein 1 chaperonin 10,Heat shock 10 kDa protein 1,Heat shock 10 kDa protein 1 chaperonin 10,Heat shock protein family E (Hsp10) member,Heat-shock 10-kD protein,mitochondrial,Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 11 kDa

Observed MW: 11 kDa

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity