Rekombinanter Golgin A2 (GOLGA2) Antikörper

Produktnummer ABIN7828243

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Golgin A2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter Golgin A2 (GOLGA2) Antikörper (ABIN7828243)

Target: Golgin A2 (GOLGA2)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A770

Produktdetails

Verwendungszweck: Recombinant GOLGA2/GM130 Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000,IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Golgin A2 (GOLGA2)

Andere Bezeichnung: GOLGA2/GM130

Hintergrund: GOLGA,golgin A,GOLGA2,GM130,golgin A2,130 kDa cis Golgi matrix protein,130 kDa cis-Golgi matrix protein,Cis golgi matrix protein GM130,Gm130 autoantigen,GOGA2,GOLGA 2,Golgi autoantigen,Golgi autoantigen golgin subfamily a 2,Golgi matrix protein GM130,Golgin 95,Golgin subfamily a 2,Golgin subfamily A member 2,Golgin-95,MGC20672,SY11 protein,Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus,and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmicreticulum to the Golgi apparatus and the cell membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at thecis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgidisassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPIvesicles and thereby inhibiting transport through the Golgi apparatus during mitosis. Also plays a key role in spindle pole assembly andcentrosome organization. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 113 kDa

Observed MW: 130 kDa The actual band is not consistent with the expectation.

UniProt: Q08379

Pathways: SARS-CoV-2 Protein Interaktom