Rekombinanter FGL1 Antikörper

Produktnummer ABIN7828204

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch FGL1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter FGL1 Antikörper (ABIN7828204)

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FGL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A637

Produktdetails anti-FGL1 Antikörper

Verwendungszweck: Recombinant FGL1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human FGL1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000,IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu FGL1

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Andere Bezeichnung: FGL1

Hintergrund: FGL,Fibrinogen-like protein,Liver fibrinogen-related protein,LFIRE,HP-041,Hepassocin,HPS,HFREP-1,LFIRE-1,HFREP1,Fibrinogen-like protein 1,Liver fibrinogen-related protein 1,FGL1,Fgl1,Hepassocin,HFREP1,HFREP-1,FGL 1,Fibrinogen like 1,Fibrinogen like protein 1,Fibrinogen related protein 1,Hepatocellular carcinoma related sequence,Hepatocyte derived fibrinogen related protein 1,Hepatocyte-derived fibrinogen-related protein 1,HFREP 1,HP 041,HP041,LFIRE 1,LFIRE1,Liver fibrinogen related protein 1,MFIRE 1,MGC108569,MGC12455,MGC37822,OTTHUMP00000122468,Fibrinogen-like protein 1 (FGL1), also known as hepassocin, is a secreted protein mainly expressed in liver and its expression is further enhanced following acute liver injury. FGL1 null mice have multiple metabolic abnormalities and are more prone to develop hepatocellular carcinoma under certain experimental conditions, suggesting FGL1 has diverse functions in vivo. More recently, FGL1 was found to be highly expressed in human cancer cells and function as an inhibitory ligand for LAG3. Blockade of the FGL1-LAG3 interaction stimulates tumor immunity in mouse models. In addition, a high plasma FGL1 level in human cancer patients is associated with a poor prognosis and resistance to anti-PD-1/PD-L1 immunotherapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 36 kDa

Observed MW: 34 kDa The actual band is not consistent with the expectation.

UniProt: Q08830