Rekombinanter EIF4G1 Antikörper

Produktnummer ABIN7828190

Der Kaninchen Monoklonal anti-EIF4G1 Antikörper wird verwendet zum Nachweis von EIF4G1 in Proben von Human und Maus. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter EIF4G1 Antikörper (ABIN7828190)

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EIF4G1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A669

Produktdetails anti-EIF4G1 Antikörper

Verwendungszweck: Recombinant eIF4G1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human eIF4G1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000,IHC 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu EIF4G1

Target: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Andere Bezeichnung: eIF4G1

Hintergrund: PARK,DKFZp686A,eIF 4 gamma,eIF-4-gamma,Eukaryotic translation initiation factor 4 gamma,IF4G,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,DKFZp686A1451,eIF 4 gamma 1,eIF 4G 1,eIF 4G1,EIF4 gamma,eIF-4G 1,eIF-4-gamma 1,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m7GTP mRNA cap and unwind the mRNA secondary structure. The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure. eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex. Moreover, eIF4G plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation. The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII). These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 175 kDa

Observed MW: 250 kDa The actual band is not consistent with the expectation.

UniProt: Q04637