Rekombinanter CD39 Antikörper

Produktnummer ABIN7828168

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CD39 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter CD39 Antikörper (ABIN7828168)

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A701

Produktdetails anti-CD39 Antikörper

Verwendungszweck: Recombinant CD39 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD39

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Andere Bezeichnung: CD39

Hintergrund: SPG,Ecto-ATP diphosphohydrolase,Ectonucleoside triphosphate diphosphohydrolase,ENTPD,ENTPD1,ATPDase,CD39,NTPDase-1,SPG64,CD 39,NTPDase1,Ecto-apyrase,Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Lymphoid cell activation antigen,NTPDase-1,CD39 antigen,DKFZp686D194,DKFZp686I093,Ecto apyrase,Ecto ATP diphosphohydrolase,Ecto-ATPase 1,Ecto-ATPDase 1,ENTP1,ENTPD 1,FLJ40921,FLJ40959,CD39,also known as ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), is a multi-pass membrane ectoenzyme that metabolizes adenosine-5'-triphosphate (ATP) to regulate purinergic signaling. Purinergic signaling by extracellular ATP and its metabolites regulate many biological processes, including vascular tone, digestion, neuronal function, and inflammation in both normal and diseased states. CD39 is expressed in endothelial cells in the vasculature to regulate local platelet purinergic signaling via metabolism of ATP to adenosine. Accordingly, CD39 regulates platelet activation aggregation and contributes to the antithrombotic properties of endothelial cells. ATP and its metabolites also finely modulate the activity of T cells and macrophages. Immunomodulation is regulated, in part, by the availability of extracellular ATP and adenosine, suggesting that CD39 may play an immunosuppressive role in the tumor microenvironment. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 58 kDa

Observed MW: 78 kDa The actual band is not consistent with the expectation.

UniProt: P49961