Rekombinanter EGR2 Antikörper

Produktnummer ABIN7828167

Der Kaninchen Monoklonal anti-EGR2 Antikörper (Klon A776) (ABIN7828167) detektiert spezifisch EGR2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter EGR2 Antikörper (ABIN7828167)

Target: EGR2 (Early Growth Response 2 (EGR2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A776

Produktdetails anti-EGR2 Antikörper

Verwendungszweck: Recombinant EGR2 Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Andere Bezeichnung: EGR2

Hintergrund: EGR,KROX,EGR2,AT591,CMT1D,CMT4E,KROX20,DKFZp686J1957,Drosophila,E3 SUMO-protein ligase EGR2,early growth response 2,Early growth response protein 2,EGR-2,FLJ14547,homolog (early growth response-2),KROX 20 Drosophila homolog,Krox 20 homolog Drosophila,KROX-20,Krox20 protein,Zinc finger protein Krox-20,EGR2 is also named as KROX20, belongs to the EGR C2H2-type zinc-finger protein family. As a zinc finger transcription factor, it is observed in both the somata and dendrites of central neurons. EGR2 plays an important role in the transient formation of hindbrain developmental compartments or rhombomeres and is also an important factor in peripheral myelination, maintenance of synaptic plasticity and long-term potentiation. EGR2 expression is induced downstream of TCR signaling in NKT precursors and EGR2 is directly connected with the key molecular checkpoints defining NKT lineage commitment and stage progression, suggesting that EGR2 not only induces the early lineage-defining transcription factor PLZF, but also controls the downstream expression of the IL-2Rβ chain. EGR2 is regulated by both soluble and membrane-bound neuregulins and its concentration is partially modulated by calcium-dependent events. EGR2/Krox20 is also required for induction of Pmp22, and is nuclear-localized. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 50 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P11161