Rekombinanter COBRA1 Antikörper

Produktnummer ABIN7828123

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch COBRA1 in WB, IHC, IP und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter COBRA1 Antikörper (ABIN7828123)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: A786

Produktdetails anti-COBRA1 Antikörper

Verwendungszweck: Recombinant NELF-B Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:10000-1:20000,IHC 1:100,FCM 1:100,IP 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: NELF-B

Hintergrund: KIAA,COBRA,NELFB,COBRA1,NELF-B,KIAA1182,NELF-B is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNApolymerase II. The NELF complex causes transcriptional pausing and is counteracted by the P-TEFb kinase complex. It may be able toinduce chromatin unfolding. NELF-B is a modulator of ligand dependent and independent expression of estrogen receptor-α target genes.NELF-B expression is reduced in metastatic and recurrent breast cancer, suggesting that low levels of NELF-B in breast cancers may serveas an indicator for poor prognosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 66 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: Q8WX92