Rekombinanter Claudin 1 Antikörper

Produktnummer ABIN7828115

Der Kaninchen Monoklonal anti-Claudin 1 Antikörper wird verwendet zum Nachweis von Claudin 1 in Proben von Human. Er wurde validiert für WB, IHC und IP.

Kurzübersicht für Rekombinanter Claudin 1 Antikörper (ABIN7828115)

Target: Claudin 1 (CLDN1)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: A187

Produktdetails anti-Claudin 1 Antikörper

Verwendungszweck: Recombinant Claudin-1 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human Claudin-1 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: Claudin-1

Hintergrund: UNQ,PRO,CLD,CLDN1,CLD1,ILVASC,SEMP1,claudin-1,Claudin1,CLD 1,CLDN 1,SEMP 1,Senescence associated epithelial membrane protein,Senescence associated epithelial membrane protein 1,Senescence-associated epithelial membrane protein,UNQ481,PRO944,claudin-1,CLD1,ILVASC,SEMP1,Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 22 kDa

Observed MW: 18 kDa The actual band is not consistent with the expectation.

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C