Rekombinanter CHD4 Antikörper

Produktnummer ABIN7828114

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CHD4 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter CHD4 Antikörper (ABIN7828114)

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CHD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A649

Produktdetails anti-CHD4 Antikörper

Verwendungszweck: Recombinant CHD4 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human CHD4 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000,IHC 1:50-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CHD4

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Andere Bezeichnung: CHD4

Hintergrund: CHD,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP dependent chromatin remodeler and a major subunit of the repressive NuRD complex. This complex plays key roles in transcriptional regulation and reorganization and maintenance of chromatin structure, as it targets pericentromeric heterochromatin and has recently been implicated in DNA damage repair, being rapidly recruited to DNA double strand breaks. CHD4 is a novel BRIT1 binding partner that regulates the HR repair process, which is a critical pathway of repairing DNA double strand breaks and plays an essential role in maintaining genomic integrity. The calculated molecular weight of CHD4 is 218 kDa, but modified CHD4 is about 250-280 kDa. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 218 kDa

Observed MW: 280 kDa The actual band is not consistent with the expectation.

UniProt: Q14839